par Danis, André 
Référence Bulletin de l'Académie royale de médecine de Belgique, 129, 2, page (173-198)
Publication Publié, 1974
Référence Bulletin de l'Académie royale de médecine de Belgique, 129, 2, page (173-198)
Publication Publié, 1974
Article révisé par les pairs
| Résumé : | There is still an unsettled controversy between the protagonists of the theory of osteoblasts and those who claim that ossification is the result of an induction phenomenon on connective tissue. From clinical observation and animal experiments, the existence of a dual mechanism is confirmed. Bone marrow is osteogenic: the different evolution between autologous and homologous marrow grafts demonstrates that new bone is issued from the transplanted cells and not from the recipient. The ossification of a piece of bone marrow in a diffusion chamber is demonstrative because the participation of surrounding tissue is eliminated. A second feature is the presence of medullary cells in the blood. This explains the presence of bone marrow in experimental and human ectopic bones, and also the similar evolution from woven bone to ossicle in bone marrow grafts and in ectopic human bone. |
