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Development of an organ failure score in acute liver failure for transplant selection and identification of patients at high risk of futility.

par Figorilli, Francesco;Putignano, Antonella ;Roux, Olivier;Houssel-Debry, Pauline;Francoz, Claire;Paugam-Burtz, Catherine;Soubrane, Olivier;Agarwal, Banwari;Durand, François;Jalan, Rajiv
Référence PloS one, 12, 12, page (e0188151)
Publication Publié, 2017

Article révisé par les pairs

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Résumé :

King's College Hospital criteria are currently used to select liver transplant candidates in acetaminophen-related acute liver failure (ALF). Although widely accepted, they show a poor sensitivity in predicting pre-transplant mortality and cannot predict the outcome after surgery. In this study we aimed to develop a new prognostic score that can allow patient selection for liver transplantation more appropriately and identify patients at high risk of futile transplantation.