Article révisé par les pairs
Résumé : Having previously found that aluminum hydroxide, used to decrease stomach acidity, has several adverse effects, we here exam-ined the effects of a mixture of calcium and magnesium carbonates, a medicine also used as an antacid, taking again ants as models. Aluminum is not present in the living organisms while calcium and magnesium carbonates are. Unfortunately and unexpectedly, these carbonates induced many adverse effects. They decreased the ants’ food consumption, general activity, orientation ability, trail following, audacity, tactile (pain) perception, cognition, escaping ability, conditioning, short and middle-term memory. However, they did not affect the ants’ social relationship. The ants never adapted themselves to these adverse effects which even increased over the consumption of these carbonates. The ants developed no dependence on their consumption of carbonates, the effect of which slowly and linearly decreased over time after weaning, and vanished after 10 to 14 hours. Consequently, aluminum hydroxide nor the mix-ture calcium and magnesium carbonates are safe drugs. They should be used only in case of severe stomach pain, and during a short time period. For moderate pain and/or long time periods, natural alternatives should be researched for treating patients suffering from excess of stomach acidity.