Titre:
  • Targeting prohibitin with small molecules to promote melanogenesis and apoptosis in melanoma cells.
Auteur:Djehal, Amel; Krayem, Mohammad; Najem, Ahmad; Hammoud, Hassan; Cresteil, Thierry; Nebigil, Canan C.G.; Wang, DONGMEI; Yu, Peng; Bentouhami, Embarek; Atassi, Ghanem; Désaubry, Laurent
Informations sur la publication:European journal of medicinal chemistry, 155, page (880-888)
Statut de publication:Publié, 2018-07
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:Cancer
ERK
Eumelanogenesis
LC3
MITF
Melanoma
Prohibitins
Triazine
MeSH keywords:Antineoplastic Agents -- chemistry -- pharmacology
Apoptosis -- drug effects
Cell Proliferation -- drug effects
Dose-Response Relationship, Drug
Drug Screening Assays, Antitumor
Humans
Melanocytes -- drug effects
Melanoma -- drug therapy -- pathology
Molecular Structure
Repressor Proteins -- chemistry -- pharmacology
Small Molecule Libraries -- chemistry -- pharmacology
Structure-Activity Relationship
Tumor Cells, Cultured
Note générale:SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:0223-5234
info:doi/10.1016/j.ejmech.2018.06.052
info:pii/S0223-5234(18)30543-9
info:scp/85049074855
info:pmid/29960207