Pregnancies during and after trastuzumab and/or lapatinib in patients with human epidermal growth factor receptor 2-positive early breast cancer: analysis from the NeoALTTO (BIG 1-06) and ALTTO (BIG 2-06) trials.

Lambertini, Matteo; Martel, Samuel; Campbell, Christine; Guillaume, Sébastien; Hilbers, Florentine FS; Schuehly, Uwe; Korde, Larissa; Abdel Azim, Hatem Hamdy; Di Cosimo, Serena; Tenglin, Richard RC; Huober, Jens; Baselga, José; Moreno-Aspitia, Alvaro; Piccart-Gebhart, Martine; Gelber, Richard D; de Azambuja, Evandro; Ignatiadis, Michail

doi:doi/10.1002/cncr.31784

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Article révisé par les pairs

Résumé :

Limited data exist on the safety of using anti-human epidermal growth factor receptor 2 (HER2) targeted agents during pregnancy. To date, only retrospective studies have assessed the prognosis of patients with a pregnancy after prior early breast cancer, with no data in HER2-positive patients.

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