Titre:
  • Epigenetic plasticity of hTERT gene promoter determines retinoid capacity to repress telomerase in maturation-resistant acute promyelocytic leukemia cells.
Auteur:Azouz, Abdulkader; Wu, Y-L; Hillion, J; Tarkanyi, I; Karniguian, A; Aradi, J; Lanotte, Michele; Chen, G-Q; Chehna, M; Ségal-Bendirdjian, E
Informations sur la publication:Leukemia, 24, 3, page (613-622)
Statut de publication:Publié, 2010-03
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Acetylation
CCCTC-Binding Factor
Cell Cycle Proteins -- genetics
Cell Line, Tumor
CpG Islands
DNA Methylation
Epigenesis, Genetic
Genes, myc
Histones -- metabolism
Humans
Leukemia, Promyelocytic, Acute -- enzymology -- genetics -- pathology
Nuclear Proteins -- genetics
Promoter Regions, Genetic
RNA Polymerase II -- metabolism
Repressor Proteins -- genetics
Sp1 Transcription Factor -- genetics
Telomerase -- antagonists & inhibitors -- genetics
Tretinoin -- pharmacology
Langue:Anglais
Identificateurs:urn:issn:0887-6924
info:doi/10.1038/leu.2009.283
info:pii/leu2009283
info:pmid/20072159