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Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules.

par Christensen, Erik I;Devuyst, Olivier;Dom, Geneviève ;Nielsen, Rikke;Van der Smissen, Patrick;Verroust, Pierre;Leruth, Michèle;Guggino, William B;Courtoy, Pierre Joseph
Référence Proceedings of the National Academy of Sciences of the United States of America, 100, 14, page (8472-8477)
Publication Publié, 2003-07

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Titre:	Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules.
Auteur:	Christensen, Erik I; Devuyst, Olivier; Dom, Geneviève; Nielsen, Rikke; Van der Smissen, Patrick; Verroust, Pierre; Leruth, Michèle; Guggino, William B; Courtoy, Pierre Joseph
Informations sur la publication:	Proceedings of the National Academy of Sciences of the United States of America, 100, 14, page (8472-8477)
Statut de publication:	Publié, 2003-07
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Absorption
	Animals
	Blood Proteins -- metabolism
	Cell Polarity
	Chloride Channels -- deficiency -- genetics -- physiology
	Endocytosis
	Endosomes -- metabolism
	Fanconi Syndrome -- metabolism
	Hydrogen-Ion Concentration
	Immunohistochemistry
	Ion Transport
	Kidney Tubules, Proximal -- metabolism -- ultrastructure
	Ligands
	Low Density Lipoprotein Receptor-Related Protein-2 -- genetics -- metabolism
	Male
	Mice
	Mice, Knockout
	Microvilli -- metabolism
	Protein Transport
	RNA, Messenger -- biosynthesis
	Receptors, Cell Surface -- genetics -- metabolism
	rab GTP-Binding Proteins -- metabolism
	rab5 GTP-Binding Proteins -- metabolism
Langue:	Anglais
Identificateurs:	urn:issn:0027-8424
	info:doi/10.1073/pnas.1432873100
	info:pii/1432873100
	info:pmid/12815097
	PMC166253