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SENSIBILITE DES KLEBSIELLA AUX ANTIBIOTIQUES. ETUDE DE 50 SOUCHES PROVENANT DE SEPTICEMIES 'EXTRA' ET 'INTRAHOSPITALIERES'

par Trolin, C.;Schoutens, ELISABETH;Yourassowsky, Eugène
Référence PATH.BIOL., 21, 6, page (581-585)
Publication Publié, 1973

Article révisé par les pairs

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Résumé :

The sensitivity to antibacterial substances of 50 strains of Klebsiella, isolated by blood culture during the period 1967 to 1971, was determined by the disk method and by determination of mean inhibitory concentrations. All strains were sensitive to gentamicin (MIC ≤ 1.56 μg/ml) and to a lesser extent to trimethoprim (MIC ≤ 3.12 μg/ml). 54% of Klebsiella strains were sensitive to cefalotin and 28% to sulfamethoxazole. There exists a synergy between trimethoprim and sulfamethoxazole. 26% of the strains were inhibited by chloramphenicol, kanamycin and tetracycline. They were isolated almost exclusively in cases of septicemia outside the hospital. A discrepancy between the disk method and the measurement of MIC was observed in 6% of cases for trimethoprim and in 15% of cases for cefalotin.