• Citer

Oxidation sensitivity may be a useful tool for the detection of the hematotoxic potential of newly developed molecules: application to antipsychotic drugs

par Kauffmann, Jean-Michel ;Liégeois, Jean-François;Bruhwyler, Jacques;Petit, Christine ;Damas, Jacques;Delarge, Jacques;Geczy, Joseph;Lamy, Maurice;Meltzer, Herbert;Mouithys-Mickalad, Ange
Référence Archives of Biochemistry and Biophysics, 370, 1, page (126-137)
Publication Publié, 1999

Article révisé par les pairs

• Détails
• Contenu

Titre:	Oxidation sensitivity may be a useful tool for the detection of the hematotoxic potential of newly developed molecules: application to antipsychotic drugs
Auteur:	Kauffmann, Jean-Michel; Liégeois, Jean-François; Bruhwyler, Jacques; Petit, Christine; Damas, Jacques; Delarge, Jacques; Geczy, Joseph; Lamy, Maurice; Meltzer, Herbert; Mouithys-Mickalad, Ange
Informations sur la publication:	Archives of Biochemistry and Biophysics, 370, 1, page (126-137)
Statut de publication:	Publié, 1999
Sujet CREF:	Chimie analytique
Mots-clés:	Agranulocytosis
	Antipsychotic
	Clozapine
	Oxidation
	Predictiv e model
	Pyridobenzazepine
MeSH keywords:	Agranulocytosis -- chemically induced
	Anemia, Aplastic -- chemically induced
	Antipsychotic Agents -- chemistry
	Antipsychotic Agents -- pharmacokinetics
	Antipsychotic Agents -- toxicity
	Benzazepines -- chemistry
	Benzazepines -- pharmacokinetics
	Benzazepines -- toxicity
	Electron Spin Resonance Spectroscopy
	Hematologic Diseases -- chemically induced
	Horseradish Peroxidase -- metabolism
	Humans
	Oxidation-Reduction
	Pyrimidinones -- chemistry
	Pyrimidinones -- pharmacokinetics
	Pyrimidinones -- toxicity
	Structure-Activity Relationship
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0003-9861
	info:doi/10.1006/abbi.1999.1380
	info:pii/S0003-9861(99)91380-2
	info:scp/0342280928
	info:pmid/10496986
	jmk-0109