Article révisé par les pairs
Résumé : Polarographic reduction of minoxidil (lxl0-5 - 5x10-4 M) and spectrophotometric study were carried out at different pH;s pK values of the acid-base equilibria were calculated using both techniques. In addition, detection limits and sensitivity were determined using electrochemical (tast, differential pulse and pseudoderivative pulse polarography) and spectrophotometric techniques. A simple method is described for the determination of this compound in pharmaceutical formulations. Electrochemical oxidation was also performed at carbon paste and at lipid modified carbon paste electrodes. © 1991, Taylor & Francis Group, LLC. All rights reserved.