Titre:
  • Overexpression of Toll-like receptor 4 amplifies the host response to lipopolysaccharide and provides a survival advantage in transgenic mice.
Auteur:Bihl, Franck; Salez, Laurent; Beaubier, Magali; Torres, David; Larivière, Line; Laroche, Line; Benedetto, Alexandre; Martel, Dominic; Lapointe, Jean-Martin; Ryffel, Bernhard; Malo, Danielle
Informations sur la publication:The Journal of immunology, 170, 12, page (6141-6150)
Statut de publication:Publié, 2003-06
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Adjuvants, Immunologic -- biosynthesis -- genetics -- physiology
Animals
Cell Membrane -- genetics -- immunology -- metabolism
Cells, Cultured
Crosses, Genetic
Flow Cytometry
Gene Dosage
Gene Expression Regulation -- immunology
Injections, Intraperitoneal
Lipopolysaccharides -- administration & dosage -- pharmacology
Lymphocyte Activation -- immunology
Membrane Glycoproteins -- biosynthesis -- genetics -- physiology
Mice
Mice, Inbred C3H
Mice, Inbred C57BL
Mice, Transgenic
Receptors, Cell Surface -- biosynthesis -- genetics -- physiology
Reverse Transcriptase Polymerase Chain Reaction
Salmonella Infections, Animal -- genetics -- immunology -- mortality -- pathology
Shock, Septic -- genetics -- immunology -- mortality
Survival Rate
Toll-Like Receptor 4
Toll-Like Receptors
Transgenes -- immunology
Langue:Anglais
Identificateurs:urn:issn:0022-1767
info:pmid/12794144