par Buisseret, Laurence
;Pommey, Sandra;Allard, Bertrand;Garaud, Soizic
;Bergeron, M.;Cousineau, I;Ameye, L.;Bareche, Yacine
;Paesmans, Marianne
;Crown, John;Di Leo, Angelo
;Loi, Sherene
;Piccart-Gebhart, Martine
;Willard-Gallo, Karen
;Sotiriou, Christos
;Stagg, John
Référence Annals of oncology
Publication Publié, 2017-11









Référence Annals of oncology
Publication Publié, 2017-11
Article révisé par les pairs
Résumé : | CD73 is an ecto-enzyme that promotes tumor immune escape through the production of immunosuppressive extracellular adenosine in the tumor microenvironment. Several CD73 inhibitors and adenosine receptor antagonists are being evaluated in phase I clinical trials. |