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BRAF Mutation Correlates With High-Risk Langerhans Cell Histiocytosis and Increased Resistance to First-Line Therapy.

par Héritier, Sébastien;Emile, Jean-François;Barkaoui, Mohamed-Aziz;Thomas, Caroline;Fraitag, Sylvie;Boudjemaa, Sabah;Renaud, Florence;Moreau, Anne;Peuchmaur, Michel;Chassagne-Clement, Catherine;Dijoud, Frédérique;Rigau, Valérie;Moshous, Despina;Lambilliotte, Anne;Mazingue, Françoise;Kebaili, Kamila;Miron, Jean;Jeziorski, Eric;Plat, Geneviève;Aladjidi, Nathalie;Ferster, Alina ;Pacquement, Hélène;Galambrun, Claire;Brugières, Laurence;Leverger, Guy;Mansuy, Ludovic;Paillard, Catherine;Deville, Anne;Armari-Alla, Corinne;Lutun, Anne;Gillibert-Yvert, Marion;Stephan, Jean Louis;Cohen-Aubart, Fleur;Haroche, Julien;Pellier, Isabelle;Millot, Frédéric;Lescoeur, Brigitte;Gandemer, Virginie;Bodemer, Christine;Lacave, Roger;Hélias-Rodzewicz, Zofia;Taly, Valérie;Geissmann, Frédéric;Donadieu, Jean
Référence Journal of clinical oncology, 34, 25, page (3023-3030)
Publication Publié, 2016-09

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Titre:	BRAF Mutation Correlates With High-Risk Langerhans Cell Histiocytosis and Increased Resistance to First-Line Therapy.
Auteur:	Héritier, Sébastien; Emile, Jean-François; Barkaoui, Mohamed-Aziz; Thomas, Caroline; Fraitag, Sylvie; Boudjemaa, Sabah; Renaud, Florence; Moreau, Anne; Peuchmaur, Michel; Chassagne-Clement, Catherine; Dijoud, Frédérique; Rigau, Valérie; Moshous, Despina; Lambilliotte, Anne; Mazingue, Françoise; Kebaili, Kamila; Miron, Jean; Jeziorski, Eric; Plat, Geneviève; Aladjidi, Nathalie; Ferster, Alina; Pacquement, Hélène; Galambrun, Claire; Brugières, Laurence; Leverger, Guy; Mansuy, Ludovic; Paillard, Catherine; Deville, Anne; Armari-Alla, Corinne; Lutun, Anne; Gillibert-Yvert, Marion; Stephan, Jean Louis; Cohen-Aubart, Fleur; Haroche, Julien; Pellier, Isabelle; Millot, Frédéric; Lescoeur, Brigitte; Gandemer, Virginie; Bodemer, Christine; Lacave, Roger; Hélias-Rodzewicz, Zofia; Taly, Valérie; Geissmann, Frédéric; Donadieu, Jean
Informations sur la publication:	Journal of clinical oncology, 34, 25, page (3023-3030)
Statut de publication:	Publié, 2016-09
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Adolescent
	Adrenal Cortex Hormones -- administration & dosage
	Antineoplastic Combined Chemotherapy Protocols -- pharmacology -- therapeutic use
	Child
	Child, Preschool
	Cohort Studies
	Drug Resistance, Neoplasm
	Female
	France -- epidemiology
	Histiocytosis, Langerhans-Cell -- drug therapy -- enzymology -- epidemiology -- genetics
	Humans
	Infant
	Infant, Newborn
	Male
	Molecular Targeted Therapy
	Mutation
	Proto-Oncogene Proteins B-raf -- antagonists & inhibitors -- genetics
	Registries
	Vinblastine -- administration & dosage
Langue:	Anglais
Identificateurs:	urn:issn:0732-183X
	info:doi/10.1200/JCO.2015.65.9508
	info:pii/JCO.2015.65.9508
	info:pmid/27382093
	PMC5321082