Titre:
  • Chronic Brucella infection induces selective and persistent interferon gammadependent alterations of marginal zone macrophages in the spleen
Auteur:Machelart, Arnaud; Khadrawi, Abir; Demars, Aurore; Willemart, Kevin; De Trez, Carl; Letesson, Jean-Jacques; Muraille, Eric
Informations sur la publication:Infection and immunity, 85, 11, e00115-17
Statut de publication:Publié, 2017
Sujet CREF:Parasitologie
Microbiologie et protistologie [bacteriol.,virolog.,mycolog.]
Immunologie
Pathologie maladies infectieuses
Mots-clés:Brucella melitensis
Brucellosis
Infection
Low-grade Th1 inflammation
Marginal zone macrophages
Spleen
MeSH keywords:Animals
Anti-Bacterial Agents -- pharmacology
B-Lymphocytes -- immunology -- microbiology
Brucella abortus -- drug effects -- immunology -- pathogenicity
Brucella melitensis -- drug effects -- immunology -- pathogenicity
Brucella suis -- drug effects -- immunology -- pathogenicity
Brucellosis -- drug therapy -- genetics -- immunology -- microbiology
Chemokine CCL19 -- genetics -- immunology
Chemokine CCL21 -- genetics -- immunology
Chemokine CXCL13 -- genetics -- immunology
Chronic Disease
Gene Expression Regulation
Host-Pathogen Interactions
Interferon-gamma -- genetics -- immunology
Macrophages -- immunology -- microbiology
Mice
Mice, Inbred C57BL
Mice, Knockout
RNA, Messenger -- genetics -- immunology
Receptors, Interferon -- deficiency -- genetics -- immunology
Receptors, Tumor Necrosis Factor, Type I -- deficiency -- genetics -- immunology
Rifampin -- pharmacology
Signal Transduction
Spleen -- immunology -- microbiology
Streptomycin -- pharmacology
T-Lymphocytes -- immunology -- microbiology
Note générale:SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:0019-9567
info:doi/10.1128/IAI.00115-17
info:pii/IAI.00115-17
info:scp/85031921317
info:pmid/28808159
PMC5649024