Titre:
  • Mepolizumab or Placebo for Eosinophilic Granulomatosis with Polyangiitis.
Auteur:Wechsler, M.E.; Akuthota, Praveen; Jayne, David R.W.David; Khoury, Paneez; Klion, Amy; Langford, Carol A; Merkel, Peter PA; Moosig, Frank; Specks, Ulrich; Cid, Maria MC; Luqmani, Raashid; Brown, Judith; Mallett, Stephen; Philipson, Richard; Yancey, Steve SW; Steinfeld, Jonathan; Weller, Peter F; Gleich, Gerald J; EGPA Mepolizumab Study Team, Florence; Roufosse, ; et al.
Informations sur la publication:The New England journal of medicine, 376, 20, page (1921-1932)
Statut de publication:Publié, 2017
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Adult
Antibodies, Monoclonal, Humanized -- adverse effects -- therapeutic use
Churg-Strauss Syndrome -- drug therapy -- immunology
Disease-Free Survival
Double-Blind Method
Drug Therapy, Combination
Eosinophils
Female
Glucocorticoids -- therapeutic use
Humans
Immunologic Factors -- adverse effects -- therapeutic use
Injections, Subcutaneous -- adverse effects
Intention to Treat Analysis
Leukocyte Count
Male
Middle Aged
Recurrence
Remission Induction
Langue:Anglais
Identificateurs:urn:issn:0028-4793
info:doi/10.1056/NEJMoa1702079
info:pmid/28514601
PMC5548295