par Cammaerts Tricot, Marie-Claire
Référence EC Nutrition, 11, 3, page (99-116)
Publication Publié, 2017
Article révisé par les pairs
Résumé : We previously showed that the largely used analgesic paracetamol has several adverse effects, impacts the central nervous system,and leads to habituation as well as dependence. An extract of the rhizome of Curcuma longa is known for having analgesic properties,and may thus be used instead of paracetamol if it has no or very few adverse effects. Examining this food complement exactlyas we examined paracetamol, we discovered that it is entirely safe. Contrary to paracetamol, it did not impact the ants’ orientationability, trail following behavior, cognition, as well as visual and olfactory conditioning and memory. Like paracetamol, it did not affectthe ants’ food consumption, general activity, audacity, relationship with brood and congeners, escaping ability. Moreover, curcumaleaded to no habituation (its effect remained intact over time) and to no dependence. It has an obvious analgesic effect. The lattereffect persisted intact for about 5 hours after weaning, then decreased slowly over time, and vanished in a total of 11 - 13 hours afterweaning, while the effect of paracetamol rapidly vanished in 4 hours. We thus recommend the use of curcuma instead of paracetamolfor reducing pain perception, however without abuse since perceiving pain is an essential physiological trait informing the organismof some health problem