par Cammaerts Tricot, Marie-Claire 
Référence MOJ biology and medicine, 1, 3, 00013
Publication Publié, 2017
Référence MOJ biology and medicine, 1, 3, 00013
Publication Publié, 2017
Article révisé par les pairs
| Résumé : | Hypercholesterolemia is nowadays one of the most widespread pathology. It is treated using statins (for instance, simvastatin) which have, however, several harmful effects. Having confirmed such effects working on ants as models, we here used again ants for examining the adverse effects of the natural red yeast of rice, a food complement which contains a statin, the lovastatin.The product used (arterin) slightly increased the ants’ intake of sugar food comparatively with meat intake, slightly decreased their activity, slightly increased their sinuosity of movement, decreased their trail following behaviour, tactile perception, cognition, ability in escaping from an enclosure, as well as their visual and olfactory conditioning and memory. Arterin did not impact the ants’ orientation ability, audacity, brood caring, aggressiveness against nest mates and aliens. Adaptation occurred for some adverse effects, habituation to the physiological impact did not occur, and ants developed no dependence on that food complement. The effects of arterin slowly decreased in 25 hours. On the whole, arterin presented less adverse effects than simvastatin, and those presented were of lower intensity. The red yeast of rice should thus be used preferentially to manufactured statins for treating predominating persons suffering from moderate hypercholesterolemia. |
