Titre:
  • A genetic variant of the sperm-specific SLO3 K(+) channel has altered pH and Ca(2+) sensitivities.
Auteur:Geng, Yanyan; Ferreira, Juan J; Dzikunu, Victor; Butler, Alice; Lybaert, Pascale; Yuan, Peng; Magleby, Karl KL; Salkoff, Lawrence; Santi, Celia CM
Informations sur la publication:The Journal of biological chemistry, 292, 21, page (8978-8987)
Statut de publication:Publié, 2017-05
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:calcium sensitivity
fertilization
genetic variant
human SLO3
pH sensitivity
patch clamp
potassium channel
reproduction
sperm
spermatozoa
MeSH keywords:Alleles
Amino Acid Substitution
Animals
Calcium -- metabolism
Evolution, Molecular
Fertility -- genetics
Humans
Hydrogen-Ion Concentration
Ion Channel Gating -- genetics
Large-Conductance Calcium-Activated Potassium Channels -- genetics -- metabolism
Male
Mice
Mutation, Missense
Potassium Channels, Voltage-Gated -- genetics -- metabolism
Spermatozoa -- metabolism
Langue:Anglais
Identificateurs:urn:issn:0021-9258
info:doi/10.1074/jbc.M117.776013
info:pii/M117.776013
info:pmid/28377504
PMC5448129