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Synthesis of 2‐amino‐4‐mercapto‐s‐triazine (5‐aza‐thiocytosine)

par De Lannoy, J.;Hinkens, Raymonde
Référence Bulletin des Sociétés chimiques belges, 81, 1, page (587-594)
Publication Publié, 1972

Article révisé par les pairs

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Résumé :

2‐Amino‐4‐mercapto‐s‐triazine (IV), an analog of cytosine, has been prepared from cyanuric chloride by a three steps synthesis and by cyclisation of guanylthiourea with ethyl formate. The mass spectra of compounds III, IV and V have been investigated and fragmentation patterns are presented which account for most of the major ions. Preliminary biological tests are reported. Copyright © 1972 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim