par Nitelet, Antoine 
;Wouters, J.;Dewez, Damien ;Evano, Gwilherm
Référence Organic letters, 19, page (6276-6279)
Publication Publié, 2017
;Wouters, J.;Dewez, Damien ;Evano, Gwilherm Référence Organic letters, 19, page (6276-6279)
Publication Publié, 2017
Article révisé par les pairs
| Résumé : | An efficient procedure for the copper-catalyzed cross-coupling between a broad range of cyanamides and iodoalkenes is reported. Upon reaction with catalytic amounts of copper(I) iodide and 2,2'-bisimidazole in the presence of cesium car-bonate in DMF at 80 °C, a fast, regioselective, and stereoretentive cross-coupling occurs. This reaction, which was found to have a broad substrate scope, provides the first general entry to N-alkenyl-cyanamides, building blocks that hold great syn-thetic potential. |
