Titre:
  • JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis and Insulin Resistance in Obesity.
Auteur:Litwak, Sara A; Pang, Lokman; Galic, Sandra; Igoillo Esteve, Mariana; Stanley, William J; Turatsinze, Jean Valéry; Loh, Kim; Thomas, Helen H.E.; Sharma, Arpeeta; Trepo, Eric; Moreno, Christophe; Gough, Daniel J; Eizirik, Decio; de Haan, Judy B; Gurzov, Esteban Nicolas
Informations sur la publication:Diabetes
Statut de publication:Publié, 2017-09
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Animals
Bcl-2-Like Protein 11 -- physiology
Cells, Cultured
Enzyme Activation
Fatty Acids -- metabolism
Fatty Liver -- etiology
Humans
Insulin Resistance
JNK Mitogen-Activated Protein Kinases -- physiology
Liver -- metabolism
Mice
Mice, Inbred C57BL
Obesity -- metabolism
Oxidative Stress
Reactive Oxygen Species -- metabolism
Note générale:SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:0012-1797
info:doi/10.2337/db17-0348
info:pii/db17-0348
info:scp/85035316628
info:pmid/28928277