par Gervy Decoster, Christine ;Dumont, Jacques Emile
Référence Biochemical pharmacology, 34, 9, page (1429-1433)
Publication Publié, 1985-05
Référence Biochemical pharmacology, 34, 9, page (1429-1433)
Publication Publié, 1985-05
Article révisé par les pairs
Résumé : | Carbamylcholine, through calcium, enhances cyclic-GMP accumulation and depresses cyclic-AMP accumulation in TSH stimulated dog thyroid. The results presented show that compounds which can be transformed to nitric oxide increase cyclic-GMP accumulation in the dog thyroid. These compounds do not require extracellular calcium for their action. In thyroid stimulated by TSH, these compounds do not depress AMP accumulation. Cyclic-GMP is not the main intracellular signal involved in the negative regulation of cyclic-AMP levels in dog thyroid. © 1985. |