par De Smul, André 
;De Waele, Boudewijn;Wissocq, P.;Kiekens, Rita
Référence Digestion, 11, 1-2, page (39-50)
Publication Publié, 1974
;De Waele, Boudewijn;Wissocq, P.;Kiekens, RitaRéférence Digestion, 11, 1-2, page (39-50)
Publication Publié, 1974
Article révisé par les pairs
| Résumé : | The actions of intravenous secretin injection and of intraduodenal acid infusion were studied in conscious rats who had recovered from the operative procedure and were maintained at a normal body temperature. The basal secretion calculated per unit weight of pancreas was higher in the rat than in the dog, even when the basal endogenous secretin stimulation induced by gastric acid was suppressed by ligation of the pylorus. Intravenous injection of GIH secretin induced a doserelated increase in volume and bicarbonate outputs. A brief washing out of proteins occurred initially. The maximal secretory response to endogenous stimulation was less than after intravenous secretin injection. The rate of secretin release was the limiting factor of the endogenously stimulated secretion. Calculated per unit weight of gland, the maximal secretory response of the pancreas to secretin is smaller in the rat than in the dog. © 1974 by S. Karger AG, Basel. |
