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Photometric Flow Injection Determination of Psychotropic Drugs: Brotizolam and Midazolam

par Gallo, Blanca;Alonso, Rosa M.;Vicente, Francisca;Viré, Jean-Claude ;Patriarche, Gaston
Référence Analytical letters, 21, 7, page (1211-1220)
Publication Publié, 1988

Article révisé par les pairs

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Résumé :

Brotizolam and Midazolam, psychotropic drugs belonging to thienotriazolodiazepine and imidazobenzodiazepine families, have been determined by flow injection analysis with photometric detection. At pH 7, signals showed to be rectilinear from 1.27 × 10-6 M to 1.07 × 10-4 for brotizolam and from 1.53 × 10-6 M to 1.07 × 10-4 M for midazolam. Methods developed were applied to the determination of both drugs in their formulations (Lendormin and Dormicum). © 1988, Taylor & Francis Group, LLC. All rights reserved.