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CDK4 phosphorylation status and a linked gene expression profile predict sensitivity to Palbociclib

par Raspé, Eric ;Coulonval, Katia ;Pita, Jaime Miguel ;Paternot, Sabine ;Rothé, Françoise ;Twyffels, Laure ;Brohée, Sylvain ;Ruscas-Craciun, Ligia Ioana ;Larsimont, Denis ;Kruys, Véronique ;Sandras, FLAVIENNE ;Salmon, Isabelle ;Van Laere, Steven;Piccart-Gebhart, Martine ;Ignatiadis, Michail ;Sotiriou, Christos ;Roger, Pierre P.
Référence EMBO molecular medicine, 9, 8, page (1052-1066), e201607084
Publication Publié, 2017-05-31

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Titre:	CDK4 phosphorylation status and a linked gene expression profile predict sensitivity to Palbociclib
Auteur:	Raspé, Eric; Coulonval, Katia; Pita, Jaime Miguel; Paternot, Sabine; Rothé, Françoise; Twyffels, Laure; Brohée, Sylvain; Ruscas-Craciun, Ligia Ioana; Larsimont, Denis; Kruys, Véronique; Sandras, FLAVIENNE; Salmon, Isabelle; Van Laere, Steven; Piccart-Gebhart, Martine; Ignatiadis, Michail; Sotiriou, Christos; Roger, Pierre P.
Informations sur la publication:	EMBO molecular medicine, 9, 8, page (1052-1066), e201607084
Statut de publication:	Publié, 2017-05-31
Sujet CREF:	Sciences biomédicales en général
Mots-clés:	breast cancer / CDK4/6 inhibitors / cyclin-dependent kinase 4 / PD0332991 / sensitivity biomarker
MeSH keywords:	Antineoplastic Agents -- pharmacology
	Breast Neoplasms -- pathology
	Cell Cycle -- drug effects
	Cell Line, Tumor
	Cyclin-Dependent Kinase 4 -- antagonists & inhibitors -- chemistry
	Female
	Humans
	Microarray Analysis
	Phosphorylation
	Piperazines -- pharmacology
	Protein Kinase Inhibitors -- pharmacology
	Protein Processing, Post-Translational
	Pyridines -- pharmacology
	Transcriptome
Note générale:	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:1757-4676
	info:doi/10.15252/emmm.201607084
	info:pii/emmm.201607084
	info:scp/85019992204
	info:pmid/28566333
	PMC5538335