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Nodular regenerative hyperplasia in HIV-positive patients: A case series and review of the literature

par Mateus Figueiredo, Ana Cristina ;Nkuize, Marcel ;Mulkay, Jean-Pierre ;De Wit, Stéphane ;Restrepo Gomez, Marcela ;Serste, Thomas
Référence Acta Gastro-Enterologica Belgica (English ed.), 80, 1, page (15-19)
Publication Publié, 2017

Article révisé par les pairs

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Résumé :

Nodular regenerative hyperplasia (NRH) is a well-described condition that leads to non-cirrhotic portal hypertension and is histologically characterised by a nodular transformation of the liver without fibrosis. It seems to be a consequence of obliterative portal venopathy of small hepatic veins. Its precise aetiology remains to be clearly determined. NRH was reported to occur in HIV-positive patients ten years ago. In this article, three consecutive clinical cases of HIV-related NRH were identified in a high volume reference centre of HIV positive patients and are presented. Clinical, diagnostic aspects and strategies for management of this under-diagnosed medical condition in the HIV population are also developed.