par Theunissen, Cédric ;Wang, Jianjun ;Evano, Gwilherm
Référence Chemical science, 8, 5, page (3465-3470)
Publication Publié, 2017
Article révisé par les pairs
Résumé : An efficient and broadly applicable process for the direct alkylation of C-H bonds in heteroarenes, privileged scaffolds in many areas of science, is reported. This reaction is based on the copper-catalyzed addition of alkyl radicals generated from activated secondary and tertiary alkyl bromides to a wide range of arenes including furans, thiophenes, pyrroles and their benzo-fused derivatives as well as coumarins and quinolinones.