par Jacquemin, Paul 
;Striuckmans, P.
Référence International journal of cancer, 36, 5, page (535-539)
Publication Publié, 1985
;Striuckmans, P.Référence International journal of cancer, 36, 5, page (535-539)
Publication Publié, 1985
Article révisé par les pairs
| Résumé : | Human sera from normal and leukemic individuals were found to contain various amounts of an antigen with determinants related to pI5E and reverse transcriptase of retroviruses. Using a specific monoclonal antibody and the immuno‐affinity purified antigen, we surveyed a series of sera and plasmas from normal individuals and hematological patients by competition radioimmunoassays and binding assays directed against this specific protein. It was detected in all the samples at various levels. The level of this 74‐kd glycoprotein appeared to be related to a stimulation of the hematopoietic system. No free antibodies were found that could recognize the labelled purified antigen. Only immune complexes prepared from the blood of some hematological patients contained the specific antigen, but complexes prepared from the blood of normal individuals did not. Copyright © 1985 Wiley‐Liss, Inc., A Wiley Company |
