par Neve, Pierre 
;Wollman, Seymour S.H.
Référence The Anatomical record, 171, 2, page (259-272)
Publication Publié, 1971
;Wollman, Seymour S.H.Référence The Anatomical record, 171, 2, page (259-272)
Publication Publié, 1971
Article révisé par les pairs
| Résumé : | The mature ultimobranchial follicle of the rat consists of two or more layers of cells (U cells) surrounding a lumen containing cell debris. The ultrastructure of the outer, or basal, U cell is characterized by the presence of half desmosomes on the basal plasma membrane and pinocytotic vesicles near it, by little granular reticulum but an abundance of free ribosomes, by clusters of fibrils connected to desmosomes and possibly free in the cytoplasm. The cell ages by accumulation of clusters of fibrils and it undergoes differentiation to form more apical U cells which contain fewer ribosomes and have fibrils dispersed in the cytoplasm. The apical U cell is desquamated into the lumen and ultimately becomes a carcass containing a dense matting of fibers and vacuoles containing a reticulated material resembling that in the lumen. U cells are observed associated with typical thyroid epithelium in the thyroid of the newborn rat in relatively large follicles containing colloid and desquamated cells. They also form rods of cells in the very young rat. Mixed follicles containing both U cells and typical thyroid epithelium occur at all ages. Copyright © 1971 Wiley‐Liss, Inc. |
