par Heilporn, Sylvie
;Broeders, Fabienne
;Daloze, Désiré
;Braekman, Jean Claude
;Boeynaems, Jean-Marie 
Référence Bulletin des Sociétés chimiques belges, 103, 7-8, page (309-319)
Publication Publié, 1994





Référence Bulletin des Sociétés chimiques belges, 103, 7-8, page (309-319)
Publication Publié, 1994
Article révisé par les pairs
Résumé : | About 30 analogues of BAPTA‐AM, a potential antithrombotic agent, have been synthesized and tested for their effect on the production of prostacyclin. None of them was found to be a better enhancer of the production of prostacyclin by aortic endothelial cells than BAPTA‐AM itself. The enhancing effect can be produced by compounds unable to chelate Ca2+, thus confirming that it is not related to their buffering capacity for free Ca2+. Copyright © 1994 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim |