par Heilporn, Sylvie ;Broeders, Fabienne ;Daloze, Désiré ;Braekman, Jean Claude ;Boeynaems, Jean-Marie
Référence Bulletin des Sociétés chimiques belges, 103, 7-8, page (309-319)
Publication Publié, 1994
Référence Bulletin des Sociétés chimiques belges, 103, 7-8, page (309-319)
Publication Publié, 1994
Article révisé par les pairs
Résumé : | About 30 analogues of BAPTA‐AM, a potential antithrombotic agent, have been synthesized and tested for their effect on the production of prostacyclin. None of them was found to be a better enhancer of the production of prostacyclin by aortic endothelial cells than BAPTA‐AM itself. The enhancing effect can be produced by compounds unable to chelate Ca2+, thus confirming that it is not related to their buffering capacity for free Ca2+. Copyright © 1994 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim |