par Pecher, Jacques 
;Martin, Richard
Référence Bulletin des Sociétés chimiques belges, 66, 1, page (545-564)
Publication Publié, 1957
;Martin, Richard Référence Bulletin des Sociétés chimiques belges, 66, 1, page (545-564)
Publication Publié, 1957
Article révisé par les pairs
| Résumé : | The syntheses of five basically substituted urethans (III to VII), five basically thio‐ureas and one basically substituted urea are described. These new products have been obtained by condensation of dialkylaminoethylamines resp. with ethyl chloroformate, phenylisothiocyanate and N‐diethylcarbamyl chloride. It is pointed out how these products may be related to the powerful filaricidal drug «Hetrazan» (Lederle Lab. div.). Biological tests, carried out on the five urethans, with Litosomoides carinii infested cotton rats, show toxicity to be high and filaricidal action negligible. Copyright © 1957 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim |
