par Van Den Bril, Marc 
;Fuks, Robert
Référence Bulletin des Sociétés chimiques belges, 89, 6, page (433-439)
Publication Publié, 1980
;Fuks, Robert Référence Bulletin des Sociétés chimiques belges, 89, 6, page (433-439)
Publication Publié, 1980
Article révisé par les pairs
| Résumé : | A number of N‐t‐butylpropenamidines V have beer, prepared for the first time by amination of N‐t‐butylacrylonitrilium [IIIb] or N‐t‐butylmethacrylonitrilium tetrachloroferrate (IIIc). The salts IIIb and IIIc are easely prepared at −40°C within a few minutes from the corresponding nitrile, t‐butyl chloride and ferric chloride. The amination [with primary or secondary aliphatic or aromatic amines] should be started at −70 °C to ensure a smooth reaction and to give high yields of amidine V, because the nitrilium salts are unstable above −10 °C. This method represents an easy one‐pot synthesis of N‐t‐butyl substituted propenamidines from the corresponding nitrile I. Copyright © 1980 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim |
