par Jank, Korneel ;De Hemptinne, Jean ;Swietochowski, André ;Demeester, Michel
Référence Journal of applied physiology, 38, 4, page (730-735)
Publication Publié, 1975
Article révisé par les pairs
Résumé : A system suitable for prolonged continuous in vivo measurement of human arterial P(O2) is described. The system uses a polarographic electrode developed by Kimmich and Kreuzer, inserted in a specially made shunt between the radial artery and an antecubital vein. The electrode surface is maintained in a fixed position parallel to the flow of blood; blood velocity dependency is small, owing to the high flow rate achieved (more than 40 cm/s); clotting is prevented by the material used and the continuous instillation of heparin through the arterial end of the shunt. The system was tested in vitro; it is stable (variations less than 0.5% in 24 h), linear and precise (± 0.2%) in a broad range of P(O2) values (from about 10 mmHg to more than 700 mmHg); its response time is 0.4 s per 95% of deflection. It was applied to 35 patients for periods ranging between 6 and 24 h; most of the patients were ventilated by an Engstrom respirator.