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Ubiquitin D Regulates IRE1alpha/c-Jun N-terminal Kinase (JNK) Protein-dependent Apoptosis in Pancreatic Beta Cells.

par Brozzi, Flora ;Gerlo, Sarah;Grieco, Fabio Arturo ;Juusola, Matilda;Balhuizen, Alexander ;Lievens, Sam;Gysemans, Conny;Bugliani, Marco;Mathieu, Chantal;Marchetti, Piero;Tavernier, Jan;Eizirik, Decio
Référence The Journal of biological chemistry, 291, 23, page (12040-12056)
Publication Publié, 2016-06

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Titre:	Ubiquitin D Regulates IRE1alpha/c-Jun N-terminal Kinase (JNK) Protein-dependent Apoptosis in Pancreatic Beta Cells.
Auteur:	Brozzi, Flora; Gerlo, Sarah; Grieco, Fabio Arturo; Juusola, Matilda; Balhuizen, Alexander; Lievens, Sam; Gysemans, Conny; Bugliani, Marco; Mathieu, Chantal; Marchetti, Piero; Tavernier, Jan; Eizirik, Decio
Informations sur la publication:	The Journal of biological chemistry, 291, 23, page (12040-12056)
Statut de publication:	Publié, 2016-06
Sujet CREF:	Sciences bio-médicales et agricoles
Mots-clés:	IRE1α
	apoptosis
	c-Jun N-terminal kinase (JNK)
	cytokinesis
	endoplasmic reticulum stress (ER stress)
	type 1 diabetes
	ubiquitin D
MeSH keywords:	Aged
	Aged, 80 and over
	Animals
	Apoptosis
	Blotting, Western
	Cell Line
	Cell Line, Tumor
	Cells, Cultured
	Cytokines -- pharmacology
	Endoribonucleases -- genetics -- metabolism
	Female
	Gene Expression -- drug effects
	HEK293 Cells
	Humans
	Insulin-Secreting Cells -- drug effects -- metabolism
	JNK Mitogen-Activated Protein Kinases -- metabolism
	Male
	Middle Aged
	Protein Binding
	Protein-Serine-Threonine Kinases -- genetics -- metabolism
	RNA Interference
	Rats
	Reverse Transcriptase Polymerase Chain Reaction
	Ubiquitins -- genetics -- metabolism
	Young Adult
Langue:	Anglais
Identificateurs:	urn:issn:0021-9258
	info:doi/10.1074/jbc.M115.704619
	info:pii/M115.704619
	info:pmid/27044747
	PMC4933257