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Complete amino acid sequence of the Mu heavy chain of a human IgM immunoglobulin

par Putnam, Frank F.W.;Florent, Gérard ;Paul, Claudine ;Shinoda, Tomotaka;Shimizu, Akira
Référence Science, 182, 4109, page (287-290)
Publication Publié, 1973

Article révisé par les pairs

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Résumé :

The amino acid sequence of the μ chain of a human IgM immunoglobulin, including the location of all disulfide bridges and oligosaccharides, has been determined. The homology of the constant regions of immunoglobulin μ, γ, α, and ε heavy chains reveals evolutionary relationships and suggests that two genes code for each heavy chain.