Cell cycle deregulation and TP53 and RAS mutations are major events in poorly differentiated and undifferentiated thyroid carcinomas.

Pita, Jaime Miguel; Figueiredo, Inês Filipa; Moura, Margarida Maria; Leite, Valeriano; Cavaco, Branca Maria

doi:doi/10.1210/jc.2013-1512

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Cell cycle deregulation and TP53 and RAS mutations are major events in poorly differentiated and undifferentiated thyroid carcinomas.

par Pita, Jaime Miguel

;Figueiredo, Inês Filipa ;Moura, Margarida Maria ;Leite, Valeriano ;Cavaco, Branca Maria
Référence The Journal of clinical endocrinology and metabolism, 99, 3, page (E497-E507)
Publication Publié, 2014-03

Article révisé par les pairs

Résumé :

Anaplastic thyroid carcinomas (ATCs) are among the most lethal malignancies, for which there is no effective treatment.

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