par Biot, Christophe 
;Delhaes, Laurence;Abessolo, Huguette;Domarle, Olivier;Maciejewski, Lucien;Mortuaire, Marlène;Delcourt, Philippe;Deloron, Philippe;Camus, Daniel;Dive, Daniel;Brocard, Jacques
Référence Journal of organometallic chemistry, 589, 1, page (59-65)
Publication Publié, 1999
;Delhaes, Laurence;Abessolo, Huguette;Domarle, Olivier;Maciejewski, Lucien;Mortuaire, Marlène;Delcourt, Philippe;Deloron, Philippe;Camus, Daniel;Dive, Daniel;Brocard, JacquesRéférence Journal of organometallic chemistry, 589, 1, page (59-65)
Publication Publié, 1999
Article révisé par les pairs
| Résumé : | The synthesis, characterization and antimalarial activity of two new ferrocene-chloroquine compounds are reported. One of them, 7-chloro-4-N-[(4-N′-ethyl-N′-ferrocenylmethyl)ammonio-1- methylbutylamino]quinolin-1-ium bi-tartrate (2) showed very promising antimalarial activity in vivo on mice infected with Plasmodium berghei N. and Plasmodium yoelii NS. and in vitro against chloroquine resistant-strains of Plasmodium falciparum. © 1999 Elsevier Science S.A. |
