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Predicting transcription factor binding sites using local over-representation and comparative genomics.

par Defrance, Matthieu ;Touzet, Hélène
Référence BMC bioinformatics, 7, page (396)
Publication Publié, 2006

Article révisé par les pairs

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Résumé :

Identifying cis-regulatory elements is crucial to understanding gene expression, which highlights the importance of the computational detection of overrepresented transcription factor binding sites (TFBSs) in coexpressed or coregulated genes. However, this is a challenging problem, especially when considering higher eukaryotic organisms.