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Assessment of an automatic determination of left ventricular dP/dt from Doppler spectra of mitral regurgitation

par Carlier, Stéphane ;Verdonck, Pascal;Dimmer, Carlo;Vandenbossche, Jean Luc
Référence Computers in cardiology, page (321-324)
Publication Publié, 1995

Article révisé par les pairs

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Résumé :

Left ventricular (LV) pressure can be derived non invasively from the continuous wave Doppler spectra of a mitral regurgitation using the simplified Bernoulli equation. The peak of its first derivative (dP/dt) reflects LV systolic function. Presently, it can be computed on profiles digitised tediously by hand tracings. This paper describes an evaluation of peak dP/dt based on the automatic determination of the contour of regurgitant velocity profiles after digitisation of raw Doppler signals with an A/D board and a PC. This method has been validated in vitro on a pulse duplicator in which a leaking mitral prosthesis was studied under several hemodynamic conditions. The Doppler derived peak dP/dt was well correlated (r2=0.9, SEE=251mmHg) with the measured one. Also recordings on patients showed a good correlation with the mean (1-3 m/s) dP/dt (r2=0.7, SEE=365mmHg), showing a systematic underestimation (199±176mmHg). In conclusion, our method is an easy and reliable tool to measure peak LV dP/dt.