par Reinhold, Heinrich ;Hildebrand Mathieu, M.;Rucquoi, Michel ;Bollaert, André
Référence Acta Anaesthesiologica Belgica, 24, 3, page (241-255)
Publication Publié, 1973
Article révisé par les pairs
Résumé : Attention is drawn to the high frequency of local thrombophlebitis complications after intravenous infusions or injections. The pH of the solutions seems to be not as important as generally thought. The density (in relation to the density of blood, d = 1.05) of the injected fluid appears to be more important, as well as the laminar flow type, which is the only possible one when injecting drugs or solutions intravenously. Only at the contact surface of this laminar flow is exchange and neutralization possible. The problem could be resolved by two improvements: By multiplying the number of laminar flows, thus creating a much larger contact surface area between the solution and the blood. This can be achieved by means of a new type of needle or catheter with several lateral holes at the tip. By using solutions with approximately the same density as the circulating blood. In this way the injected solutions will stay in the middle of the vessel and possible differences of osmotic pressure or pH could no longer be harmful for the endothelial cells of the vein wall.