Article révisé par les pairs
Résumé : A post mortem histologic examination of the eyes of a man of 35 with primary hyperoxaluria revealed crystals in the ciliary processes and at the level of the retinal pigment epithelium. Crystallography demonstrated that they consisted of wewhellite. The ocular lesions were compared with those found by other authors in primary hyperoxaluria, after prolonged methoxyflurane anesthesia, after experimental administration of dibutyloxalic acid or naphthalene, and in the human retina in longstanding detachments. Most of the factors which give rise to the presence in the eye of oxalate and its selective precipitation in the midst of certain ocular tissues remain hypothetical. The retinal lesions observed in primary hyperoxaluria appear to be pathognomonic for hyperoxalemia. Further autopsy findings were nephrocalcinosis, miliary tuberculosis, transplanted kidney (7 mth before death), crystals in heart muscle and liver sinusoids; death from respiratory insufficiency.