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Lipase and bile salts in the small intestine of the dog: Relation to lipid absorption

par Kiekens, Rita;Wissocq, P.;Govaerts, Jean
Référence Digestion, 4, 5, page (295-308)
Publication Publié, 1971

Article révisé par les pairs

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Résumé :

Lipase activity, bile salt concentration and intraluminal phase of lipid resorption are investigated in 4 different regions of the dog small intestine. Lipase activity remains constant throughout the first half of the small intestine but drops to low values in the distal small gut. Conjugated bile salts concentration rises progressively from the duodenum until the upper limit of the distal quarter of the small bowel is reached, where it commences to drop until zero is reached at the end of the small bowel. In the duodenum the low pH (<6.3) often limits solubilization of hydrolyzed lipids. More optimal conditions occur in the proximal jejunum where most of the lipids are absorbed. The factors governing the intraluminal phase of lipid resorption cover a greater length of intestine than would be necessary for a normal resorption. © 1971 S. Karger AG, Basel.