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Impaired early insulin response to glycemic stimulus during enflurane anesthesia in dogs

par Camu, Frédéric
Référence Acta Anaesthesiologica Belgica, 27, page (267-271)
Publication Publié, 1976

Article révisé par les pairs

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Résumé :

When compared to the awake control dogs enflurane administration induced glucose intolerance with mild hyperglycemia resulting from decreased basal insulin secretion. Moreover, insulin secretion in response to a glycemic stimulus (intravenous glucose tolerance test) was impaired. Comparison between the net incremental insulin responses and the cumulative insulinogenic indexes suggests impaired insulin secretion is mainly related to a deficit in secretion from the acutely releasable insulin storage pool.