par de Castro, Gilberto;D'Inverno, Emile 
;Lecron, Luc
Référence Anesthésie, analgésie, réanimation, 37, 1-2, page (17-24)
Publication Publié, 1980
;Lecron, Luc Référence Anesthésie, analgésie, réanimation, 37, 1-2, page (17-24)
Publication Publié, 1980
Article révisé par les pairs
| Résumé : | Synthetic morphinoid drugs and endorphines have similar effects on the C.N.S. Opiate receptors are situated on the spinal cord, in the grey matter, and also in small quantity in the white matter. So, logically, local injections of exogenous morphinoids, mixed with local anaesthetic drugs, should increase analgesia (an interesting effect of this kind of anaesthesia is the cardiovascular stability that it induces). The authors have chosen a synthetic morphinoid, fentanyl: small molecular, high liposolubility, non ionized; use of morphine basis is very delicate because of its powerful effects in the C.S.F. For spinal anaesthesia, hypertonic glucose solution (10%) is added to obtain hyperbaric effect and localized anaesthesia. Analgesia is characteristically increased and of longer duration. Cardiovascular system is well controlled (blood pressure, peripheral dilatation, regular pulse). The action on the white fibers of the C.N.S. is not explained. This study will be continued because this analgesia can bring some interesting effects in medullar anaesthesia. |
