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The Belgian ten-center open label trial of topical 2% minoxidil solution in early male pattern alopecia

par Roseeuw, Diane;Decroix, Jacques;Delescluse, Jacques ;Delune, Michel;Gheeraert, Patrick ;Franchimont, Claudine;Luytens, I.;Teunissen, L.;Vandaele, R.
Référence International journal of dermatology, 27, Supplément S6, page (452-455)
Publication Publié, 1988-07

Article révisé par les pairs

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Résumé :

In this 24-week, open-label study, the safety and efficacy of topically applied 2% minoxidil solution were evaluated in the treatment of early male pattern alopecia. One hundred forty-nine male patients applied 1 ml of the test solution twice daily throughout the study. From baseline to week 24, statistically significant increases in all hair counts were observed. Nearly half (47%) of the patients achieving new hair growth believed that they had achieved cosmetically acceptable moderate to dense hair growth. Investigators believed that 44% of the patients achieving new hair growth had a similar response. Little change was observed in vital signs, and no abnormal findings were observed in electrocardiograms, echocardiograms, or chest roentgenograms. Two patients dropped out during the final week of the study due to dermatologic events. This study supports previous findings on the safe and effective use of minoxidil solution in the treatment of early male pattern alopecia.