Titre:
  • An In-Depth Comparison of Latency-Reversing Agent Combinations in Various in vitro and ex vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression.
Auteur:Darcis, Gilles; Kula, Anna; Bouchat, Sophie; Fujinaga, Koh; Corazza, Francis; Ait-Ammar, Amina; Delacourt, Nadège; Melard, Adeline; Kabeya, Kabamba; Vanhulle, Caroline; Van Driessche, Benoît; Gatot, Jean-Stéphane; Cherrier, Thomas; Pianowski, Luiz F.; Gama, Lucio; Schwartz, Christian; Vila, Jorge; Burny, Arsène; Clumeck, Nathan; Moutschen, Michel; De Wit, Stéphane; Peterlin, Matija; Rouzioux, Christine; Rohr, Olivier; Van Lint, Carine
Informations sur la publication:PLoS pathogens, 11, 7, e1005063
Statut de publication:Publié, 2015
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Bryostatins -- pharmacology
CD4-Positive T-Lymphocytes -- drug effects -- virology
Diterpenes -- metabolism
Gene Expression Regulation, Viral -- drug effects
HIV-1 -- drug effects -- physiology
Humans
Positive Transcriptional Elongation Factor B -- metabolism
Virus Activation -- drug effects
Virus Latency -- drug effects
Note générale:SCOPUS: ar.j
Langue:Français
Identificateurs:urn:issn:1553-7374
info:doi/10.1371/journal.ppat.1005063
info:pii/PPATHOGENS-D-15-00502
info:scp/84938795129
info:pmid/26225566
PMC4520688