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An In-Depth Comparison of Latency-Reversing Agent Combinations in Various in vitro and ex vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression (O. Rohr and C. Van Lint are co-last authors).

par Darcis, Gilles ;Kula, Anna ;Bouchat, Sophie ;Fujinaga, Koh;Corazza, Francis ;Ait-Ammar, Amina;Delacourt, Nadège ;Melard, Adeline;Kabeya, Kabamba ;Vanhulle, Caroline ;Van Driessche, Benoît ;Gatot, Jean-Stéphane ;Cherrier, Thomas;Pianowski, Luiz F.;Gama, Lucio;Schwartz, Christian;Vila, Jorge;Burny, Arsène ;Clumeck, Nathan ;Moutschen, Michel;De Wit, Stéphane ;Peterlin, Matija;Rouzioux, Christine;Rohr, Olivier;Van Lint, Carine
Référence PLoS pathogens, 11, 7, e1005063
Publication Publié, 2015

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Titre:	An In-Depth Comparison of Latency-Reversing Agent Combinations in Various in vitro and ex vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression (O. Rohr and C. Van Lint are co-last authors).
Auteur:	Darcis, Gilles; Kula, Anna; Bouchat, Sophie; Fujinaga, Koh; Corazza, Francis; Ait-Ammar, Amina; Delacourt, Nadège; Melard, Adeline; Kabeya, Kabamba; Vanhulle, Caroline; Van Driessche, Benoît; Gatot, Jean-Stéphane; Cherrier, Thomas; Pianowski, Luiz F.; Gama, Lucio; Schwartz, Christian; Vila, Jorge; Burny, Arsène; Clumeck, Nathan; Moutschen, Michel; De Wit, Stéphane; Peterlin, Matija; Rouzioux, Christine; Rohr, Olivier; Van Lint, Carine
Informations sur la publication:	PLoS pathogens, 11, 7, e1005063
Statut de publication:	Publié, 2015
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Bryostatins -- pharmacology
	CD4-Positive T-Lymphocytes -- drug effects -- virology
	Diterpenes -- metabolism
	Gene Expression Regulation, Viral -- drug effects
	HIV-1 -- drug effects -- physiology
	Humans
	Positive Transcriptional Elongation Factor B -- metabolism
	Virus Activation -- drug effects
	Virus Latency -- drug effects
Note générale:	SCOPUS: ar.j
Langue:	Français
Identificateurs:	urn:issn:1553-7374
	info:doi/10.1371/journal.ppat.1005063
	info:pii/PPATHOGENS-D-15-00502
	info:scp/84938795129
	info:pmid/26225566
	PMC4520688