par Kleiner, Henri ;Stavric, Vl;Yager, Michèle
Référence Journal de gynécologie obstétrique et biologie de la reproduction, 5, 1, page (25-37)
Publication Publié, 1976
Article révisé par les pairs
Résumé : Plasma cystinylaminopeptidase (CAP) activity and 24 hr urinary excretion of oestrogens were measured simultaneously in 102 pathological pregnancies. The correlation between the two chemical assays is weak (rho=0.13 to 0.47). Plasma CAP levels were significantly (p<0.01) lowered in cases of fetal death; but urinary oestrogen assays were within the normal limits (p<0.1) in this group. Each assay suggested an equal number of correct or incorrect prognoses. Their association resulted in 9 correct prognoses in 12 pregnancies with unfavourable outcome, but led to 12 unduly bad prognoses in a group of 40 normal births. The association of the two assays allows a more adequate diagnosis of high-risk pregnancies, but has the disadvantage of offering an unduly bad prognosis in a greater number of normal cases.