par Brohée, Dany 
;Delcourt, André
Référence Acta gastro-enterologica Belgica (Ed. multilingue), 40, 9-10, page (317-328)
Publication Publié, 1977
;Delcourt, André Référence Acta gastro-enterologica Belgica (Ed. multilingue), 40, 9-10, page (317-328)
Publication Publié, 1977
Article révisé par les pairs
| Résumé : | Macroamylasemia is in rare instances the cause of benign persisting hyperamylasemia. Its nature and its pathological significance are not totally cleared up; in some cases we are dealing with a complex amylase-immunoglobulin (IgG or IgA), in others with a complex amylase-chelating substance (protein, glycoprotein or polysaccharide). Macroamylasemia is most frequently associated with chronic alcoholism and with intestinal malabsorption; sometimes it exists in normal subjects. Macroamylasemia may be easily identified by measuring the ratio clearance of amylase/clearance of endogenous creatinine, and by performing a column-chromatography or an electrophoresis of the amylases. Its frequency is estimated at 0,5 to 1% of the overall population and at 5% of the cases of hyperamylasemia. |
