par Thys, Jean-Pierre 
;Cornil, Arnaud ;Smets, Philippe
Référence Acta cardiologica, 29, 1, page (19-29)
Publication Publié, 1974
;Cornil, Arnaud ;Smets, Philippe Référence Acta cardiologica, 29, 1, page (19-29)
Publication Publié, 1974
Article révisé par les pairs
| Résumé : | The evolution of 174 patients with acute myocardial infarction was compared. The patients were randomly divided into 2 groups. 85 subjects received a polarizing solution: continuous intravenous perfusion during 7 days of one liter daily of a 10% glucose solution with potassium (40 m Eq/L) and insulin (20 units); 89 patients formed the control group, receiving a slow perfusion (one liter daily) of a 5% glucose solution. Patients suffering from renal insufficiency, diabetes treated by insulin, pulmonary edema or second and third degree heart blocks were excluded from the study. The frequency of arrhythmias observed in both groups, polarized and control, was not significant. The rise in serum enzymes (glutamic oxaloacetic transaminase and creatine phosphokinase) was similar in both groups. Mortality on the 7th day (end of the polarizing treatment) was not reduced. Finally, mortality during the total stay in hospital was 16.5% for the treated group and 11.2% for the control group, showing no statistically significant difference. The comparison between the 2 groups has not demonstrated any favorable effect of the polarizing treatment. |
