Article révisé par les pairs
Résumé : 46 patients underwent surgery on the colon or rectum. They were randomly separated into 2 groups, one receiving a mechanical preparation together with lincomycine, neomycine, polymyxine, kanamycine, bacitracine and nystatine, and the other a mechanical preparation alone. Analysis of results reveals no statistically significant difference in the frequency of infections, neither local (11/24 with antibiotics vis 13/22 without), neither general (16/24 and 9/22), nor was the postoperative use of antibiotics for local or general infection different in the 2 groups. No influence of age or preoperative radio-therapy could be shown. This randomized trial suggests that there is little advantage in associating antibiotics to mechanical preparation before colorectal surgery.