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ETUDE CONTROLEE DE L'ADMINISTRATION ORALE D'ANTIBIOTIQUES COMME PREPARATION A LA CHIRURGIE DIGESTIVE

par Mendes Da Costa, Pierre ;Klastersky, Jean ;Gerard, André
Référence Acta chirurgica Belgica (Ed. bilingue), 76, 5, page (475-480)
Publication Publié, 1977

Article révisé par les pairs

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Résumé :

46 patients underwent surgery on the colon or rectum. They were randomly separated into 2 groups, one receiving a mechanical preparation together with lincomycine, neomycine, polymyxine, kanamycine, bacitracine and nystatine, and the other a mechanical preparation alone. Analysis of results reveals no statistically significant difference in the frequency of infections, neither local (11/24 with antibiotics vis 13/22 without), neither general (16/24 and 9/22), nor was the postoperative use of antibiotics for local or general infection different in the 2 groups. No influence of age or preoperative radio-therapy could be shown. This randomized trial suggests that there is little advantage in associating antibiotics to mechanical preparation before colorectal surgery.